<p>Among patients who underwent total knee arthroplasty, intra-articular tranexamic acid significantly reduced total blood loss, drainage, reduction of hemoglobin and the need for transfusion without increasing the incidence of deep venous thrombosis and pulmonary embolism, making it safe and efficacious, according to study results.</p><p>Through a search of various databases for relevant randomized, controlled trials, researchers included seven studies comprising 622 patients. The researchers calculated mean difference in total blood loss, risk ratio for transfusion and complication rate in the tranexamic acid-treated group vs. the placebo group.</p>
Fellowship-Trained, Board Certified Orthopaedic Surgeon
Specialist in Hip & Knee Surgery
Dr. Smith is a fellowship-trained, Board Certified orthopaedic surgeon with extensive training in hip & knee surgery from the prestigious Mayo Clinic in Rochester, Minnesota & the New Albany Surgical Hospital in New Albany, Ohio. He completed his Orthopedic Surgery Residency at Michigan State University & medical school..